Transport for London has warned that a 52-metre-high advertising billboard proposed for Draper House at Elephant & Castle would "exacerbate accident and collision risks" at the southern roundabout.
Large advertising billboards and wraps are planned for several buildings in SE1, including Hill House in Blackfriars Road and Sea Containers House on the South Bank.
At Draper House Remedia International wants to erect a large advertisement shroud on the scaffolding that will be set up for the refurbishment of the building. Remedia says that revenue from the 52-metre advertisement will help cover the cost of refurbishment.
The latest proposal (10/AP/1172) follows a similar application made in 2007 which was refused by Southwark Council but approved on appeal by planning inspector Terry Emm.
Mr Emm concluded that the proposed advert "would form an acceptable temporary addition to the townscape" and that the council had not provided evidence that the adjacent roundabout is "exceptionally dangerous".
This time Transport for London has objected strongly to the proposal, pointing out that the remodelling of the southern roundabout is starting imminently and that, with temporary alterations to the road layout during the course of works, drivers should not be distracted by extra advertising.
Tfl's development planning officer PakLim Wong warns that the proposal would result in an "unacceptable adverse safety impact to traffic and pedestrians in the Elephant & Castle area".
Meanwhile Tectonic Outdoor has applied to install a 14.4 metre x 11.85 metre PVC mesh advertising banner on the northern face of Hill House, a vacant office block in Blackfriars Road (10/AP/1718).
Tectonic says that the banners, which would be changed every 28 days, would contain little or no text in order to avoid distractions to motorists.
At Sea Containers House on the South Bank insurance company Aviva wants to put a huge mesh across the river frontage of the building (10/AP/1903) as part of its "You are the Big Picture" campaign which will run from October to December this year.
Aviva is taking over prominent buildings in five large cities across the world where it will display portrait photographs by Patric Shaw. Many of the images will be of children from Aviva's Street to School programme.
Southwark Council is also considering another application for a PVC mesh billboard on Borough High Street (10/AP/1560).
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