Streetcar has won the contract to launch almost 100 on-street car club bays across Southwark, including more than 30 in SE1.
Car clubs allow members to book the use of a car for as little as 30 minutes at a time online or on the phone.
Drivers access the vehicle using a smart card, enter their PIN and drive away.
Streetcar already has 12,000 members in Lambeth and Southwark, up from 7,000 a year ago.
The new bays will be introduced over the next three months, with a view to expanding the service to bring every Southwark resident within a few minutes' walk of a car club vehicle.
The first new bays have been unveiled in East Dulwich alongside 10 new cars.
"Reducing the number of privately owned cars in the borough is a key objective for Southwark Council, and figures show that for every car club vehicle there is a reduction of around 25 private cars on the road," says Cllr Paul Kyriacou, executive member for environment and transport.
"Happily, going into partnership with Streetcar like this enables us to achieve more than this objective. In addition, it means that we take another step towards reaching our carbon reduction targets thanks to the environmentally friendly effects of car clubs."
Brett Akker, Streetcar's co-founder, said: "We're delighted by this news. The scale and speed with which we're able to implement these new bays marks a step change in our work with councils. It illustrates the value the concept brings to so many Londoners, both in terms of personal cost savings and, thanks to its green credentials, to society as a whole."
Although car clubs already exist in the borough, this will be the first time that a car club operator has struck a deal with the council to allow the vehicles to be parked using on-street parking spaces.
The new bays in SE1 will be in Balaclava Road, Bermondsey Street, Curlew Street, Emerson Street, Gainsford Street, Great Guildford Street, Great Suffolk Street, Harper Road, Henley Drive, Keyworth Street, Lant Street (2 spaces), Lavington Street (2 spaces), Paris Garden, Park Street, Pocock Street (2 spaces), Rennie Street, Riley Road, Tooley Street (2 spaces), Trinity Street, Ufford Street, Union Street (2 spaces), Weston Street (2 spaces), White's Grounds, Wolseley Street and Zoar Street.
Zipcar, which has its UK offices on Borough High Street, is the other main car club operator in the UK. It already has 14 locations in SE1.
For the latest local news and events direct to your inbox every Monday, you need our weekly email newsletter SE1 Direct.
7,000+ locals read it every week. Can you afford to miss out?
Read the latest issue before signing up